CME Presentations

Dravet Syndrome



  • Kelly Knupp, MD

    Kelly Knupp, MD

    Kelly Knupp, MD

    Associate Professor of Pediatrics and Neurology

    Kelly Knupp, MD, is associate professor of pediatrics and neurology at the University of Colorado. She practices at Children’s Hospital Colorado in Aurora, where she is associate research director of the Neuroscience Institute, director of the Dravet Program, and co-interim section chief. Dr Knupp’s research interests are epileptic encephalopathies, including Dravet Syndrome. She was a founding member of the Pediatric Epilepsy Research Consortium, which focuses on developing collaborative research nationally for children with epileptic encephalopathies. Dr Knupp serves on the medical advisory boards of the Epilepsy Foundation of Colorado and the Dravet Syndrome Foundation. She received her medical degree from the University of New Mexico School of Medicine in Albuquerque.
  • Elaine C. Wirrell, MD, FRCPC

    Elaine C. Wirrell, MD, FRCPC

    Elaine C. Wirrell, MD, FRCPC

    Consultant and Chief of Pediatric Epilepsy

    Elaine C. Wirrell, MD, FRCPC, is professor of child and adolescent neurology, and consultant and chief of Pediatric Epilepsy at Mayo Clinic in Rochester, Minnesota. Dr Wirrell’s research focuses on epidemiology and the treatment of pediatric epilepsy, as well as comorbidities. Her research has led to 173 peer-reviewed articles and 19 book chapters. Dr Wirrell is chair of the AES Pediatric Content Committee and of the ICNA Research Committee, and co-chair of the ILAE Nosology and Definitions Committee Member: Pediatric Psychiatry Committee. She is a member of the Fellow of the Royal College of Physicians & Surgeons of Canada, the Minnesota Board of Medical Practice, and the American Epilepsy Society. Dr Wirrell received her medical degree from University of British Columbia in Vancouver.

CME Information

Dravet Syndrome: Best Practices for Seizure‐ and Non‐Seizure‐related Symptoms

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After completing this activity, the participant should be better able to:
  • Explain how to incorporate data from clinical trials of new antiseizure medications into the standard of care for DS management
  • Critically appraise the place in the management algorithm of DS of newly available agents to reduce seizures and enhance overall patient outcomes
  • Summarize the multidisciplinary approach to patients with DS
This activity is jointly provided by Global Education Group and PlatformQ Health Education, LLC, in collaboration with the Dravet Syndrome Foundation and the National Organization for Rare Disorders, Inc.


This activity is supported by an educational grant from Zogenix, Inc.


Wednesday, June 23, 2021 from 12:00pm – 1:00pm ET


The educational design of this activity addresses the needs of neurologists, pediatric neurologists, epileptologists, pediatric epileptologists, pediatricians, primary care providers, general practitioners, nurses, nurse practitioners, physician assistants, and pharmacists involved and/or interested in the management of patients with DS.


Dravet syndrome (DS) is among the most challenging epilepsy syndromes due to intractable seizures, recurrent status epilepticus, comorbidities such as intellectual disability, and an increased mortality rate. Prolonged or repetitive seizures diminish quality of life not only for patients, but also for parents and caregivers. Improved awareness of DS may lead to earlier diagnoses, improved seizure control and ability to reach clinically meaningful outcomes. In addition, a correct and early diagnosis can ensure that clinicians do not perform unnecessary testing, choose the best treatment available, and avoid medications that can exacerbate the condition.

Join esteemed experts Kelly Knupp, MD, MSCS and Elaine Wirrell, MD, FRCPC as they discuss the benefits of early management of DS, the place of newest options such as fenfluramine in the treatment algorithm along with practical strategies for a multidisciplinary approach to DS.


This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Global Education Group (Global) and PlatformQ Health Education, LLC. Global is accredited by the ACCME to provide continuing medical education for physicians.


Global Education Group designates this live activity for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.


Global Education Group is accredited with distinction as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation.

This educational activity for 1.0 contact hour is provided by Global Education Group. Nurses should claim only the credit commensurate with the extent of their participation in the activity.



Global Education Group is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.


Global Education Group designates this continuing education activity for 1.0 contact hour(s) (0.10 CEUs) of the Accreditation Council for Pharmacy Education. (Universal Activity Number - 0530-9999-21-094-L01-P)

This is a knowledge-based activity.


This activity should take approximately 60 minutes to complete.


In order to receive credit for this activity, the participant must (1) read the target audience, learning objectives, and disclosure statements, (2) complete the educational activity online, and (3) complete the post-test and activity evaluation. To receive AMA PRA Category 1 Credits™, participants must receive a minimum score of 70% on the post-test. For pharmacist/ACPE learners, please check the CPE monitor for your CE credit within 60 days of the activity.


Participants will need a computer with a recent version of Adobe Flash installed, as well as an internet connection sufficient for streaming media.


There is no fee for this educational activity.


Global Education Group (Global) adheres to the policies and guidelines, including the Standards for Integrity and Independence in Accredited CE, set forth to providers by the Accreditation Council for Continuing Medical Education (ACCME) and all other professional organizations, as applicable, stating those activities where continuing education credits are awarded must be balanced, independent, objective, and scientifically rigorous. All persons in a position to control the content of an accredited continuing education program provided by Global are required to disclose all financial relationships with any ineligible company within the past 24 months to Global. All financial relationships reported are identified as relevant and mitigated by Global in accordance with the Standards for Integrity and Independence in Accredited CE in advance of delivery of the activity to learners. The content of this activity was vetted by Global to assure objectivity and that the activity is free of commercial bias.

All relevant financial relationships have been mitigated.

The faculty have the following relevant financial relationships with ineligible companies:
Name of Faculty or Presenter Reported Financial Relationship
Kelly G. Knupp, MD, MSCS Associate Professor of Pediatrics and Neurology University of Colorado, Anschutz Medical Campus Consulting Fee: Biocodex, Encoded, Epygenix, Stoke, Zogenix Contracted Research: Encoded, Stoke, Zogenix
Elaine C. Wirrell, MD, FRCPC Professor of Child and Adolescent Neurology Consultant and Chief of Pediatric Epilepsy Mayo Clinic, Rochester, MN Consulting Fee (e.g., Advisory Board): Encoded, Zogenix (all monies to Mayo Clinic), GW Pharma (all monies to Mayo Clinic)

The planners and managers reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME activity:

Name of Planner or Manager Reported Financial Relationship
Ashley Marostica, RN, MSN Nothing to disclose
Lindsay Borvansky Nothing to disclose
Andrea Funk Nothing to disclose
Liddy Knight Nothing to disclose
Ashley Cann Nothing to disclose
Alissa Yost Nothing to disclose
Carole Drexel Nothing to disclose


This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. Global Education Group (Global) and PlatformQ Health Education, LLC do not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of any organization associated with this activity. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.


Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed in this activity should not be used by clinicians without evaluation of patient conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.


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